Wrong Turn

Release 2003

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Director: Rob Schmidt
Writers: Alan B. McElroy
Stars: Desmond Harrington, Eliza Dushku, Emmanuelle Chriqui, Jeremy Sisto, Kevin Zegers
IMDB: http://www.imdb.com/title/tt0295700/

Six people find themselves trapped in the woods of West Virginia, hunted down by "cannibalistic mountain men grossly disfigured through generations of in-breeding."